Category Archives: Job

Software Development Role at KCL

The role of Software Developer will be working within the Data Science and Software Development Team in the newly formed Centre for Translational Informatics (CTI) and will assume the principle role for delivery of a data harvesting platform for the Remote Assessment of Disease and Relapse (RADAR) program, a €22 million European Innovative Medicines Initiative (IMI2) to pioneer mHealth remote monitoring capabilities in 3 key neurological disease areas: Major Depression, Multiple Sclerosis and Epilepsy.

The role will require working with the other RADAR EU academic groups, technology partners (e.g. INTEL, CBITS [Northwestern University], Software AG) and pharma partners in order to carry out requirements gathering, as well as assisting with the evaluation of platform technologies and devices, and to carry out end-to-end development, deployment and maintenance of the RADAR wearable and mobile phone data harvesting platform.

The candidate will have significant software development experience and knowledge of client and server-side development, Java, JavaScript, and Android App development.

More details: https://www.hirewire.co.uk/HE/1061247/MS_JobDetails.aspx?JobID=68502

HPC Systems Administrator at the Royal Brompton

The Royal Brompton Hospital are looking for a Bioinformatician & Systems Administrator to support their growing Genetics & Genomics Laboratory. The role will be working with a dynamic and diverse team investigating the genetic basis of heart disease, supporting our HPC cluster/storage, leading on the development of a data warehousing solution for NGS data, and with scope to be involved in the research activities of the group (NGS data analysis).

Deadline 21st April 2014

Please apply here:

http://www.jobs.nhs.uk/xi/vacancy/4d30a1fa3ec5401415f8aec5fc5b6a8c/?vac_ref=913357370

Bioinformatics / Stat Gen PostDoc @ KCL

From Mike Weale:

Postdoctoral Research Associate, Bioinformatics / Statistical Genetics
King’s College London

The post-holder will spearhead computational and statistical analyses of expression quantitative trait locus (eQTL) and allele-specific expression (ASE) signals in a large and ongoing study of the genetic regulation of multiple human brain tissues. Analyses will combine genomewide SNP data with whole-transcriptome RNA-seq data. Development of novel statistical genetic methods relevant to on-going studies will be strongly encouraged.

There are many computational and statistical challenges to be addressed. Correlations in expression levels among tissues and genes will need to be adequately accounted for in the downstream analysis, as will heterogeneity in eQTL strength among tissues and among alternative transcripts for the same gene. The appointee will benefit from being part of an important internationally recognized project, and will receive support from data analysis teams at both King’s College London (KCL) and University College London (UCL).

Applications are welcome from candidates with a PhD in a relevant subject area with experience of analysing scientific data. Competency in both statistics and especially programming (HPC computing, R/python or equivalents) are essential requirements.

**Important** The KCL component of this post will last until 31 March 2015, at which point the post-holder will be invited to apply for the equivalent post at University College London for an additional 15 months. Thus while the post duration is officially 16 months, the transfer to UCL for an additional 15 months should be more or less automatic given the project-specific relevant skills that the post-holder will have at that point.

The appointment will be made, dependent on relevant qualifications, within the Grade 6 scale, currently £33,654 – £39,705 per annum, plus £2,323 London Weighting Allowance.

For informal enquiries about the post please contact Dr Michael Weale at michael.weale@kcl.ac.uk
Formal application must be through the KCL online application system, available via the KCL website for this post:
https://www.kcl.ac.uk/depsta/pertra/vacancy/internal/apply.php?id=16843956

Job Ref: WMGA94513MK
Closing date for applications: 13 Jan 2014

Bioinformatics job at the Crick

http://www.jobs.ac.uk/job/AHJ651/principal-research-associate-bioinformatics/#!

Cancer Bioinformatics Jobs in London

Couple of London-based Bioinformatics positions available:

Senior Bioinformatician in the  Gene Function Team, Inst. of Cancer Research, Chelsea, London led by Professor Alan Ashworth.

The Gene Function Laboratory currently houses over 30 scientists and runs a wide-ranging portfolio of projects including basic cancer biology and drug development programmes. As part of these projects, the laboratory interacts with a diverse range of collaborators, contract research organisations, pharmaceutical companies and funding charities.

We are seeking an experienced and motivated Senior Bioinformatician to support high- throughput cell-based screening and Next Generation Sequencing based projects within the Breakthrough Centre. The successful post holder will perform statistical analyses and quality control reporting on screen data, using publicly available packages and commercial software to facilitate the prompt and efficient transfer of data into scientific publications. The postholder will also perform next generation sequencing data analysis including read alignment and variant calling.

Experience in the analysis of RNA interference or cell-based drug screens is essential, as is the ability to apply existing third-party tools to the analysis of Next Generation Sequencing and microarray data sets.

Applicants should hold a PhD or equivalent qualification in a relevant subject, have scripting experience in R and Perl and will ideally hold a post-graduate qualification in bioinformatics.

The starting salary will be in the range £40,725 – £43,119 p.a. inclusive and the position will be offered initially on a fixed-term contract of one year.

Informal enquiries are welcome and can be made to Dr Chris Lord (chris.lord@icr.ac.uk). Please note – this address is for enquiries only and you should not send your application to this email address; CV, pdf copies of your best 3 publications over the last 5 years and covering letter must be submitted online at http://www.icr.ac.uk/jobsearch. Job Ref. No. 1279843

Closing date: 16 October 2012

Postdoctoral Research Fellow Position available in Cancer Bioinformatics at  UCL Cancer Institute and CR-UK London Research Institute

A fellowship position is available in the UCL Cancer Institute and CR-UK London Research Institute in the Swanton laboratory
http://www.london-research-institute.org.uk/research/charles-swanton
To study mechanisms of cancer genome instability, intratumour heterogeneity and drug resistance using genome wide cancer sequencing and trasncriptomic datasets in breast cancer, funded by the BCRF, building on recent work (Gerlinger et al New England Journal of Medicine 2012 and Yap and Swanton Science Translational Medicine 2012). Potential candidates will be expected to have an interest in oncology and translational research and be proficient in ‘R’ or equivalent and have a strong statistical background. Competitive London PDRF salary will be offered to the successful applicant.

Please make informal inquiries with a CV and covering letter to charles.swanton@cancer.org.uk

Bioinformatics PhDs at KCL

Bioinformatics / Clinical Informatics PhD Topics at the Institute of Psychiatry, King’s College London. Closing date for applications is 12/12/12

Contact corinne.farrugia@kcl.ac.uk for further details / application pack and see this website for more details of each project

  • Epigenetics and gene expression in Alzheimer’s
  • Investigating Unreported Adverse Effects of Psychiatric Drugs through Data-Mining of Electronic Health Records and Integration of Clinical and Genomic Data
  • Drug repositioning: the application of old drugs to new diseases/targets
  • Text mining and machine learning to identify temporal patterns in co-morbidity networks derived from clinical data
  • Integrative translational ‘omics with a special focus on mental health : bioinformatics analyses for large scale omic data integration, biomarker discovery, drug repositioning and screening for new therapeutic targets
  • A Multi-agent paradigm for Integrating Cellular Networks
  • Applying machine learning methods to develop predictive models of treatment success for patients with chronic fatigue syndrome
  • Biomarkers of pre-clinical Alzheimer’s disease

PostDoc Bioinformatics post at KCL

From Richard Dobson:

Applications are invited for the post of Research Associate in Bioinformatics to join a large team of bioinformaticians at the NIHR Specialist Biomedical Research Centre for Mental Health (BRC-MH). The BRC-MH, funded by the National Institute for Health Research, undertakes translational research into mental health disorders. The candidate will perform translational bioinformatics research of an international standard using expression profiling, genomics, proteomics and other approaches to describe disease mechanisms of mental health disorders as well as identify biomarkers of progression, disease and treatment response. A requirement will be to develop a service by applying cutting edge as well as developing novel bioinformatic approaches as part of a collaborative team.
Detail The successful candidate will ideally have a relevant PhD and a proven track record of bioinformatics research.

The appointment will be made at Grade 6, currently £31,020 – £33,884 per annum, plus £2,323 per annum London Allowance.

Apply