Prof Andrey Rzhetksy: “Computational Analysis of Complex Human Disorders”

From Jason Alvey at KCL:

You are invited to a Special Guest Lecture to be held on Thursday, 21st February 2013, at 3:30 – 4:30pm in Small Lecture Theatre, First Floor, Main Building, Institute of Psychiatry, Denmark Hill Campus.

Professor Andrey Rzhetsky, Department of Human Genetics, University of Chicago

Computational analysis of complex human disorders’

Focusing on autism, bipolar disorder and schizophrenia, my talk will touch the following questions. How understanding of genetics and epidemiology of disease can be advanced through modeling and computational analysis of very large and heterogeneous datasets?  What are the bottlenecks in analysis of complex human maladies?  How can we model and compute over multiple data types to narrow hypotheses about genetic causes of disease?  How collaborations across multiple fields of science can bring translational results to initially purely academic studies?

Andrey Rzhetsky is a Professor of Medicine and Human Genetics, at the University of Chicago. He is also a Pritzker Scholar, and a Senior Fellow of both the Computation Institute, and the Institute for Genomics and Systems Biology at the University of Chicago. His research is focused on computational analysis of complex human phenotypes in context of changes and perturbations of underlying molecular networks. The input data for these studies is supplied by large-scale mining of free text, computation over clinical records, and high-throughput systems biology experiments.  Most recently in 2011, Rzhetsky was awarded a $13.7 million grant from the National Institutes of Health titled “Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes.” This five-year project involves investigators from seven institutions across the United States and Israel who will study new computational methodology for the analysis of multiple complex mental health disorders, such as autism and schizophrenia.


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