Imperial College Centre for Integrative Systems Biology and Bioinformatics Seminar Series

All are welcome to the following CISBIO seminars – venues as listed:


Monday Feb 13th, 4.30pm
7th Floor common room
Sir Ernst Chain Building – Wolfson Laboratories (formerly Biochemistry)

Dr Guido Sanguinetti,
University of Edinburgh

Latent switching models of transcriptional regulation

Abstract: I will review the use of a class of continuous-time models of transcriptional regulation. This consist of a system of (ordinary or stochastic) differential equations whose coefficients depend on a latent, discrete state Markov Jump process. The interpretation we will propose is that the DEs describe the dynamics of expression of a set of genes, while the latent processes describe activation states of transcription factor proteins. I will describe the approach to inference, and present results on a number of real data sets.

http://homepages.inf.ed.ac.uk/gsanguin/research.html


Monday 5th March, 4 pm
G34 Lecture Theatre, SAF (Sir Alexander Fleming) building

Dr Nick Le Novère
EMBL – European Bioinformatics Institute

This or that – Allosteric Calcium Sensors and Synaptic Plasticity

http://www.ebi.ac.uk/~lenov/


Monday 12th March, 4pm
G34 Lecture Theatre, SAF (Sir Alexander Fleming) building

Dr Mario Caccamo
The Genome Analysis Centre (TGAC)

Computational analysis of next generation sequencing (provisional title)

http://www.tgac.ac.uk/bioinformatics/


Monday 26th March, 4.30pm
Rm 122, SAF (Sir Alexander Fleming) building

Prof Jürg Bähler,
University College London

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes

www.bahlerlab.info

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