Next meeting is on Wednesday the 14th April and the topic is “Computational Analysis of MeDIP Data” (Gareth Wilson)
DNA methylation represents an important epigenetic modification of mammalian genomes. Genome-wide data can be generated using the technique MeDIP-seq. In order to analyse this data, Batman (Bayesian Tool for Methylation Analysis) was developed. This algorithm, written by Thomas Down, is used to provide a quantitative estimation of absolute methylation values from MeDIP profiles.
In this tutorial I will look at the prerequisites for running Batman and discuss my experiences with using the tool. I will also briefly discuss a new methlyation analysis tool, currently in development, called Pipistrelle.
the next venue will be “John Ellis LT – The Royal London Hospital” (http://www.qmul.ac.uk/about/campus/whitechapel/index.html)
Refer to: Wall